产品名称

PMS2 Antibody

产品货号

ABB5114

其他名称

DNA mismatch repair gene; DNA mismatch repair protein PMS2; HNPCC4; PMS1 protein homolog 2;

Gene ID

Human:P54278    

SwissPro

Human:http://www.uniprot.org/uniprot/P54278    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF IP FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human PMS2

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

110kDa

产品概述

Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 t