产品名称

LRRK2 Antibody

产品货号

ABB5193

其他名称

Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin; PARK8; ROCO2; RIPK7; LRRK2

Gene ID

Human:Q5S007    

SwissPro

Human:http://www.uniprot.org/uniprot/Q5S007    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF IP

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human LRRK2

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

286kDa

产品概述

LRRK2 positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium rele