产品名称

Notch1 Antibody

产品货号

ABB5244

其他名称

NOTC1, NOTCH1, TAN1, hN1, neurogenic locus notch homolog protein 1, neurogenic locus notch homolog protein 1 precursor,

Gene ID

Human:P46531    

SwissPro

Human:http://www.uniprot.org/uniprot/P46531    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF FC

稀释比例

WB 1:500~1:3000 IHC 1:50~1:200 ICC/IF 1:100~1:500 FC 1:200~1:500

反应种属

Human Mouse

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Notch1

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

125kDa

产品概述

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH