产品名称

Phospho-Retinoblastoma (S780) Antibody

产品货号

ABB5260

其他名称

OSRC; RB; p105-Rb; pRb; RB1; pp110; Retinoblastoma 1; PPP1R130

Gene ID

Human:P06400    

SwissPro

Human:http://www.uniprot.org/uniprot/P06400    

宿主种属

Rabbit IgG

应用范围

WB IHC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Retinoblastoma

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

110kDa

产品概述

Cell cycle-dependent phosphorylation by a CDK inhibits Rb target binding and allows cell cycle progression. Rb inactivation and subsequent cell cycle progression likely requires an initial phosphorylation by cyclin D-CDK4/6 followed by cyclin E-CDK2 phosp