产品名称

Phospho-PKR (T446) Antibody

产品货号

ABB5271

其他名称

E2AK2;E2AK2; EIF2AK1; EIF2AK2; MGC126524; PKR p68 kinase; PKR; PRKR;

Gene ID

Human:P19525    

SwissPro

Human:http://www.uniprot.org/uniprot/P19525    

宿主种属

Rabbit IgG

应用范围

WB IHC IP ChIP

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-PKR (T446)

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

62kDa

产品概述

PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.