产品名称

IRF1 Antibody

产品货号

ABB5507

其他名称

Interferon regulatory factor 1; IRF1; MAR;

Gene ID

Human:P10914    

SwissPro

Human:http://www.uniprot.org/uniprot/P10914    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF IP FC

稀释比例

WB 1:500~1:1000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:50 FC 1:50

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human IRF1

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

48kDa

产品概述

Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [M