产品名称

Caspase-8 Antibody

产品货号

ABB5584

其他名称

CASP8; ALPS2B; Apoptotic protease Mch-5; Apoptotic cysteine protease; Casp-8; Caspase-8; CAP4; Caspase 8; MACH; MCH5; Pro Caspase 8; FADD-like ICE; FLICE;

Gene ID

Human:Q14790    

SwissPro

Human:http://www.uniprot.org/uniprot/Q14790    

宿主种属

Rabbit IgG

应用范围

WB

稀释比例

WB 1:500~1:2000

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Caspase-8

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

55kDa

产品概述

Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10 (1-3). Activated caspase-8 cleaves and activates downstream ef