产品名称

Daxx Antibody

产品货号

ABB5586

其他名称

Death domain-associated protein 6; Daxx; hDaxx; Fas death domain-associated protein; ETS1-associated protein 1; EAP1; DAXX; BING2; DAP6;

Gene ID

Human:Q9UER7    

SwissPro

Human:http://www.uniprot.org/uniprot/Q9UER7    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Daxx

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

110kDa

产品概述

Acts as an adapter protein in a MDM2-DAXX-USP7 complex by regulating the RING-finger E3 ligase MDM2 ubiquitination activity. Under non-stress condition, in association with the deubiquitinating USP7, prevents MDM2 self-ubiquitination and enhances the intr