产品名称

Chk1 Antibody

产品货号

ABB5619

其他名称

Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog (S. pombe); Serine/threonine-protein kinase Chk1;

Gene ID

Human:O14757     

SwissPro

Human:http://www.uniprot.org/uniprot/O14757     

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Chk1

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

54kDa

产品概述

Chk1 kinase acts downstream of ATM/ATR kinase and plays an important role in DNA damage checkpoint control, embryonic development, and tumor suppression. Activation of Chk1 involves phosphorylation at Ser317 and Ser345 and occurs in response to blocked DN