产品名称

Chk2 Antibody

产品货号

ABB5633

其他名称

CHEK2; CHK2; Cds1; Chk2; EC 2.7.11.1; RAD53; kinase Chk2;

Gene ID

Human:O96017    

SwissPro

Human:http://www.uniprot.org/uniprot/O96017    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF IP

稀释比例

WB 1:10000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Chk2

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

62kDa

产品概述

These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster d