产品名称

APC Antibody

产品货号

ABB5641

其他名称

APC; APC protein; Adenomatous polyposis coli protein; DP2.5; mAPC;

Gene ID

Human:P25054    

SwissPro

Human:http://www.uniprot.org/uniprot/P25054    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF IP

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

反应种属

Human Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human APC

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

160kDa

产品概述

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte grow