产品名称

PKR Antibody

产品货号

ABB5665

其他名称

eIF-2A protein kinase 2; Protein kinase RNA-activated; PKR; p68 kinase; P1/eIF-2A protein kinase;

Gene ID

Human:P19525    

SwissPro

Human:http://www.uniprot.org/uniprot/P19525    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF IP

稀释比例

WB 1:10000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human PKR

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

68kDa

产品概述

PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.