产品名称

Phospho-CrkII (Tyr221) Antibody

产品货号

ABB5672

其他名称

Adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; CRK; CRKII; Proto-oncogene c-Crk;

Gene ID

Human:P46108    

SwissPro

Human:http://www.uniprot.org/uniprot/P46108    

宿主种属

Rabbit IgG

应用范围

WB ICC/IF

稀释比例

WB 1:1000~1:2000 ICC/IF 1:50~1:200

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-CrkII (Tyr221)

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

42kDa

产品概述

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosi