产品名称

Phospho-Chk1 (S296) Antibody

产品货号

ABB5677

其他名称

Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog (S. pombe); Serine/threonine-protein kinase Chk1;

Gene ID

Human:O14757    

SwissPro

Human:http://www.uniprot.org/uniprot/O14757    

宿主种属

Rabbit IgG

应用范围

WB

稀释比例

WB 1:500~1:2000

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-Chk1 (S296)

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

54kDa

产品概述

Chk1 kinase acts downstream of ATM/ATR kinase and plays an important role in DNA damage checkpoint control, embryonic development, and tumor suppression. Activation of Chk1 involves phosphorylation at Ser317 and Ser345 by ATM/ATR, followed by autophosphor