产品名称

TOP1 Antibody

产品货号

ABB5725

其他名称

DNA topoisomerase 1; DNA topoisomerase I; TOP1; TOPI; topoisomerase I; type I DNA

Gene ID

Human:P11387    

SwissPro

Human:http://www.uniprot.org/uniprot/P11387    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF FC

稀释比例

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

反应种属

Human Mouse

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human TOP1

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

91kDa

产品概述

Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in