产品名称

Phospho-Raf1 (S259) Antibody

产品货号

ABB5944

其他名称

C-Raf; CRAF; Protein kinase raf 1; RAF1; Raf proto-oncogene serine/threonine-protein kinase; kinase Raf1;

Gene ID

Human:P04049    

SwissPro

Human:http://www.uniprot.org/uniprot/P04049    

宿主种属

Rabbit IgG

应用范围

WB IHC

稀释比例

WB 1:500~1:1000 IHC 1:50~1:100

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-Raf1 (S259)

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

73kDa

产品概述

Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell phy