产品名称

eIF4EBP1 Antibody

产品货号

ABB6583

其他名称

4E-BP1; 4EBP1; BP-1; MGC4316; PHAS-I;

Gene ID

Human:Q13541    

SwissPro

Human:http://www.uniprot.org/uniprot/Q13541    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF IP FC

稀释比例

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human eIF4EBP1

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

18kDa

产品概述

Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent trans