产品名称

NUMB Antibody

产品货号

ABB6686

其他名称

c14_5527; h Numb; Numb; Numb homolog; S171;

Gene ID

Human:P49757    

SwissPro

Human:http://www.uniprot.org/uniprot/P49757    

宿主种属

Rabbit IgG

应用范围

WB

稀释比例

WB 1:500~1:2000

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human NUMB

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

71kDa

产品概述

Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch