产品名称

Axin2 Antibody

产品货号

ABB6803

其他名称

Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin;

Gene ID

Human:Q9Y2T1    

SwissPro

Human:http://www.uniprot.org/uniprot/Q9Y2T1    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Axin2

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

94kDa

产品概述

Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-cat