产品名称

ITCH Antibody

产品货号

ABB6957

其他名称

ADMFD; AIF4; AIP4; Atrophin 1 interacting protein 4; Itchy homolog E3 ubiquitin protein ligase; NAPP1; NFE2 associated polypeptide 1; Ubiquitin protein ligase ITCH;

Gene ID

Human:Q96J02    

SwissPro

Human:http://www.uniprot.org/uniprot/Q96J02    

宿主种属

Rabbit IgG

应用范围

WB

稀释比例

WB 1:500~1:2000

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human ITCH

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

103kDa

产品概述

Involved in the negative regulation of MAVS-dependent cellular antiviral responses. Ubiquitinates MAVS through 'Lys-48'-linked conjugation resulting in MAVS proteosomal degradation. Involved in the regulation of apoptosis and reactive oxygen species level