产品名称

Phospho-MLKL (S358) Antibody

产品货号

ABB7146

其他名称

hMLKL; Mlkl;

Gene ID

Human:Q8NB16    

SwissPro

Human:http://www.uniprot.org/uniprot/Q8NB16    

宿主种属

Rabbit IgG

应用范围

WB IHC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-MLKL (S358)

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

54kDa

产品概述

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characteri