产品名称

TRIM25 Antibody

产品货号

ABB7155

其他名称

EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147;

Gene ID

Human:Q14258    

SwissPro

Human:http://www.uniprot.org/uniprot/Q14258    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF IP FC

稀释比例

WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:50 FC 1:60

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human TRIM25

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

71kDa

产品概述

Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial fo