产品名称

HIF1AN Antibody

产品货号

ABB8421

其他名称

FIH 1; FIH1; HIF1AN;

Gene ID

Human:Q9NWT6    

SwissPro

Human:http://www.uniprot.org/uniprot/Q9NWT6    

宿主种属

Rabbit IgG

应用范围

WB IHC ICC/IF FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:80

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human HIF1AN

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

40kDa

产品概述

Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-intera