产品名称

PAG Antibody

产品货号

ABB8795

其他名称

CBP; Csk binding protein; PAG; PAG1;

Gene ID

Human:Q9NWQ8    

SwissPro

Human:http://www.uniprot.org/uniprot/Q9NWQ8    

宿主种属

Rabbit IgG

应用范围

WB IHC IP FC

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:100

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human PAG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20

背景资料

80kDa

产品概述

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhib