产品名称

CD3 epsilon antibody

产品货号

ABB00003

基因名称

CD3E

SwissPro

Human:P07766 Mouse P22646    

宿主种属

Rabbit

应用范围

WB, IHC-P, ICC/IF, IP

稀释比例

1:50-1:200

反应种属

Mouse

克隆性

Monoclonal

克隆号

R22667

免疫原

Recombinant fragment.

同种型

IgG

保存液

pH: 7.2 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

保存条件

4°C

背景资料

Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinase

细胞定位

Membrane

细胞类型

0