产品名称

Phospho-PKR (T446) Antibody

产品货号

ABF300309

基因名称

Phospho-PKR (T446)

蛋白名称

Phospho-PKR (T446)

其他名称

E2AK2;E2AK2; EIF2AK1; EIF2AK2; MGC126524; PKR p68 kinase; PKR; PRKR;

SwissPro

Human:P19525    

宿主种属

Rabbit

应用范围

WB IHC IP ChIP

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Phospho-PKR (T446)

特异性

Phospho-PKR (T446) Antibody detects endogenous levels of total Phospho-PKR (T446)

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

62kDa

产品概述

PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.