产品名称

Src Antibody

产品货号

ABF300457

基因名称

Src

蛋白名称

Src

其他名称

EC 2.7.10.2; p60-Src; c-Src; pp60;c-src;

SwissPro

Human:P12931    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF

稀释比例

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

反应种属

Human Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human

特异性

Src Antibody detects endogenous levels of total Src

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

60kDa

产品概述

Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail