产品名称

MLKL Antibody

产品货号

ABF300491

基因名称

MLKL

蛋白名称

MLKL

其他名称

Mixed lineage kinase domain-like protein; hMLKL;

SwissPro

Human:Q8NB16    

宿主种属

Rabbit

应用范围

WB IHC

稀释比例

WB 1:500~1:2000 IHC 50~200

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human MLKL

特异性

MLKL Antibody detects endogenous levels of total MLKL

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

54kDa

产品概述

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characteri