产品名称

Cyclin E1 Antibody

产品货号

ABF300811

基因名称

Cyclin E1

蛋白名称

Cyclin E1

其他名称

CCNE; Ccne1; cyclin E variant ex5del; cyclin E variant ex7del; Cyclin E1; Cyclin Es; Cyclin Et; G1/S specific cyclin E; G1/S-specific cyclin-E1;

SwissPro

Human:P24864    

宿主种属

Rabbit

应用范围

WB ICC/IF

稀释比例

WB 1:1000~1:2000 ICC/IF 1:50~1:200

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Cyclin E1

特异性

Cyclin E1 Antibody detects endogenous levels of Cyclin E1

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

47kDa

产品概述

Cyclin E1 and cyclin E2 can associate with and activate CDK2. Upon DNA damage, upregulation/activation of the CDK inhibitors p21 Waf1/Cip1 and p27 Kip1 prevent cyclin E/CDK2 activation, resulting in G1/S arrest. Cyclin E1 is phosphorylated at multiple sit