产品名称

ADAM10 Antibody

产品货号

ABF301231

基因名称

ADAM10

蛋白名称

ADAM10

其他名称

CDw156; CD156c; ADAM10; KUZ; MADM;

SwissPro

Human:O14672    

宿主种属

Rabbit

应用范围

WB IP

稀释比例

WB 1:500~1:2000 IP 1:50

反应种属

Human Mouse Rat

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human ADAM10

特异性

ADAM10 Antibody detects endogenous levels of total ADAM10

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

84kDa

产品概述

The ADAM10 prodomain acts as a chaperone that stabilizes mature ADAM protein folding, and prevents target-protein shedding through inhibition of ADAM10 proteinase activity. Mature ADAM10 is the major α-secretase responsible for cleavage of Notch, APP, cad