产品名称

Securin Antibody

产品货号

ABF301581

基因名称

Securin

蛋白名称

Securin

其他名称

Cut2; EAP1; hPTTG; Pds1; PTTG; PTTG1; Pttg3; Securin; TUTR1;

SwissPro

Human:O95997/Q6IAL9    

宿主种属

Rabbit

应用范围

WB IHC ICC/IF IP FC

稀释比例

WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30 FC 1:50

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Securin

特异性

Securin Antibody detects endogenous levels of total Securin

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

28kDa

产品概述

Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the