产品名称

Nicastrin Antibody

产品货号

ABF301830

基因名称

Nicastrin

蛋白名称

Nicastrin

其他名称

APH2; Ncstn; NCT; Nicastrin;

SwissPro

Human:Q92542    

宿主种属

Rabbit

应用范围

WB ICC/IF

稀释比例

WB 1:500~1:2000 ICC/IF 1:50~1:200

反应种属

Human

克隆性

Monoclonal

免疫原

A synthesized peptide derived from human Nicastrin

特异性

Nicastrin Antibody detects endogenous levels of total Nicastrin

同种型

Rabbit IgG

保存液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式

Affinity-chromatography

保存条件

-20°C/1 year

背景资料

120/140kDa

产品概述

Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofact